PBR28

• Description :

  PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH) . PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies[1].

• CAS Number :

  [253307-65-2]

• UNSPSC :

  12352005

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/pbr28.html

• Purity :

  98.91

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C)N(CC1=C(OC)C=CC=C1)C2=C(OC3=CC=CC=C3)C=CN=C2

• Molecular Formula :

  C21H20N2O3

• Molecular Weight :

  348.40

• References & Citations :

  [1]Sander CY, et al. [11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow. J Cereb Blood Flow Metab. 2021 Nov;41 (11) :3069-3084.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1