Pilocarpine (nitrate) (Standard)

Pilocarpine (nitrate) (Standard)

• CAS Number: 148-72-1
• UNSPSC Description: Pilocarpine (nitrate) (Standard) is the analytical standard of Pilocarpine (nitrate). This product is intended for research and analytical applications. Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
• Target Antigen: mAChR
• Type: Reference Standards
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/pilocarpine-nitrate-standard.html
• Smiles: [O-][N+](O)=O.O=C1OC[C@H](CC2=CN=CN2C)[C@@H]1CC
• Molecular Weight: 271.27
• References & Citations: [1]Matsuzaki K, et al. Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands. FEBS Open Bio. 2017 Dec 7;8(1):85-93.|[2]Yuan XL, et al. Cytotoxicity of pilocarpine to human corneal stromal cells and its underlying cytotoxic mechanisms. Int J Ophthalmol. 2016 Apr 18;9(4):505-11.|[3]Tonta MA, et al. Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium. Br J Pharmacol. 1994 Jun;112(2):525-32.
• Shipping Conditions: Room temperature