Decorsin

• Description :

  Decorsin Catalog number: MDP0643 CAS Number: 372146-20-8 Sequence: Ala-Pro-Arg-Leu-Pro-Gln-Cys-Gln-Gly-Asp-Asp-Gln-Glu-Lys-Cys-Leu-Cys-Asn-Lys-Asp-Glu-Cys-Pro-Pro-Gly-Gln-Cys-Arg-Phe-Pro-Arg-Gly-Asp-Ala-Asp-Pro-Tyr-Cys-Glu (Disulfide bonds between Cys7-Cys15, Cys17-Cys27, and Cys22-Cys38) Amount: 100 ug Molecular Weight: 4377.6 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Krezel AM, Ulmer JS, Wagner G, Lazarus RA. Recombinant decorsin: dynamics of the RGD recognition site Protein Sci. 2000 Aug;9(8):1428-38. 2: Seymour JL, Henzel WJ, Nevins B, Stults JT, Lazarus RA. Decorsin. A potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora J Biol Chem. 1990 Jun 15;265(17):10143-7. 3: Lao X, Bao J, Yu T, Li Q, Zheng H. Structural and functional aspects of decorsin and its analog as recognized by integrin αIIbβ3 J Mol Model. 2016 Nov;22(11):281. 4: Polverino de Laureto P, Scaramella E, De Filippis V, Marin O, Doni MG, Fontana A. Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation Protein Sci. 1998 Feb;7(2):433-44. 5: Yang J, Zhan CY, Dong XC, Yang K, Wang FX. Interaction of human fibrinogen receptor (GPIIb-IIIa) with decorsin Acta Pharmacol Sin. 2004 Aug;25(8):1096-104. 6: Frare E, de Laureto PP, Scaramella E, Tonello F, Marin O, Deana R, Fontana A. Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability Protein Eng Des Sel. 2005 Oct;18(10):487-95. 7: McLane MA, Gabbeta J, Rao AK, Beviglia L, Lazarus RA, Niewiarowski S. A comparison of the effect of decorsin and two disintegrins, albolabrin and eristostatin, on platelet function Thromb Haemost. 1995 Nov;74(5):1316-22. 8: Yu M, Yu M, Ru B. Enhanced expression of an antibody-targeted plasminogen activator in Escherichia coli by fusion to decorsin Biotechnol Lett. 2004 May;26(9):717-21. 9: Krezel AM, Wagner G, Seymour-Ulmer J, Lazarus RA. Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting Science. 1994 Jun 24;264(5167):1944-7. 10: Arocha-Piñango CL, Marchi R, Carvajal Z, Guerrero B. Invertebrate compounds acting on the hemostatic mechanism Blood Coagul Fibrinolysis. 1999 Mar;10(2):43-68.
  Products Related to Decorsin can be found at Peptides

• Short Description :

  Catalog Number: MDP0643 (100 ug)

• Weight :

  0.15

• Length :

  2

• Width :

  0.5

• Height :

  0.5