Mal-Exo-EVC

CAT: 0804-HY-169352Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-169352Size:1 Each
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Description
Mal-Exo-EVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) [1].
UNSPSC
12352211
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-exo-evc.html
Smiles
CN(C(OC(C(NCCCCCN1C(C=CC1=O)=O)=O)C2=CC=C(NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C2)=O)C
Molecular Formula
C38H55N9O12
Molecular Weight
829.90
References & Citations
[1]Tomohiro Watanabe, et al. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates. J Med Chem. 2024 Oct 24;67 (20) :18124-18138.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cleavable Linker

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