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Ebastine

CAT: 0804-HY-B0674-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0674-01Size:500 mg
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Description
Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1].
CAS Number
90729-43-4
Product Name Alternative
LAS-W 090; RP64305
UNSPSC
12352005
Hazard Statement
H302, H413
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Ebastine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 58.75 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(OC(C3=CC=CC=C3)C4=CC=CC=C4)CC2
Molecular Formula
C32H39NO2
Molecular Weight
469.66
Precautions
H302, H413
References & Citations
[1]J Sastre. Ebastine in allergic rhinitis and chronic idiopathic urticarial. Allergy. 2008 Dec;63 Suppl 89:1-20.|[2]Fu-Ming Tsai, et al. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation. Biomed Res Int. 2019 Feb 11;2019:6360503.|[3]Fujii, et al. Absorption, distribution, metabolism and excretion of [14C]ebastine after a single administration in rats. Arzneimittelforschung. 1994 Apr;44 (4) :527-38.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor

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