AF 698

• Description:

  AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice[1].

• UNSPSC:

  12352005

• Target:

  Drug Derivative

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/af-698.html

• Smiles:

  O=C(OC1OC(C2=CC=CC=C21)=O)C3=C[C@@](CCC4)(CC)[C@@](N4CC5)([H])C6=C5C7=CC=CC=C7N36

• Molecular Formula:

  C28H26N2O4

• Molecular Weight:

  454.52

• References & Citations:

  [1]Marzo, et al. A new phthalidyl derivative of apovincaminic acid: (3 alpha, 16 alpha) -eburnamenine-14 carboxylic acid phthalidyl ester (AF 698) . A preliminary report on its chemical and pharmacological properties. Arzneimittel-forschung 32.6 (1982) : 601-603.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [82958-11-0]