AF 698

CAT: 0804-HY-129406Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-129406Size:1 Each
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Description
AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice[1].
CAS Number
[82958-11-0]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/af-698.html
Smiles
O=C(OC1OC(C2=CC=CC=C21)=O)C3=C[C@@](CCC4)(CC)[C@@](N4CC5)([H])C6=C5C7=CC=CC=C7N36
Molecular Formula
C28H26N2O4
Molecular Weight
454.52
References & Citations
[1]Marzo, et al. A new phthalidyl derivative of apovincaminic acid: (3 alpha, 16 alpha) -eburnamenine-14 carboxylic acid phthalidyl ester (AF 698) . A preliminary report on its chemical and pharmacological properties. Arzneimittel-forschung 32.6 (1982) : 601-603.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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