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Dihydromunduletone

CAT: 0804-HY-101483-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101483-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dihydromunduletone (DHM) is a rotenoid derivative and a selective, potent adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonist with an IC 50 of 20.9 μM for GPR56, but not inhibit GPR110 or class A GPCRs[1].
CAS Number
674786-20-0
UNSPSC
12352005
Target
Drug Derivative; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Dihydromunduletone.html
Concentration
10mM
Purity
99.23
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC1(C)C=CC2=C(OC)C(CC(C3=C(O)C=C4C(CC(O)C(C)(C)O4)=C3)=O)=CC=C2O1
Molecular Formula
C25H28O6
Molecular Weight
424.49
References & Citations
[1]Hannah M. Stoveken, et al. Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein–Coupled Receptor Antagonist. Mol Pharmacol. 2016 Sep; 90 (3) : 214–224.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T11044-01Dihydromunduletone

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