Recombinant Mouse Csf3 Protein(Trx Tag)

Recombinant Mouse Csf3 Protein(Trx Tag)

• Background: Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
• Abbreviation: Csf3
• Synonyms: CSF;TNFSF;C17orf;C17orf33;CD254;CSF3OS;Filgrastim;GCSF;G-CSF;Granulocyte colony-stimulating factor;Lenograstim;ODF (Osteoclast Differentiation Factor);OPGL;Pluripoietin;soluble Receptor Activator of NF-kB Ligand;sRNAK Ligand;TNFSF11;TRANCE (TNF-Related Activation-induced Cytokine);Csfg;Csf3
• CAS Number: 9000-83-3
• UniProt: P09920
• Accession Number: P09920
• Host: E.coli
• Origin Species: Mouse
• Tag: N-Trx
• Sequence: Val31-Ala208
• Field of Research: Immunology;Cancer;Cell Biology;Signal Transduction;Stem cells
• Endotoxin: < 10 EU/mg of the protein as determined by the LAL method
• Purity: > 95% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Form: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Calculated Molecular Weight: 39.6 kDa
• Observed Molecular Weight: 35 kDa