Mps1-IN-2
CAT:
804-HY-13994-05
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mps1-IN-2
- CAS Number: 1228817-38-6
- UNSPSC Description: Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor, with an IC50 and a Kd of 145 nM and 12 nM for Mps1 and a Kd of 61 nM for Plk1.
- Target Antigen: Mps1; Polo-like Kinase (PLK)
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Mps1-IN-2.html
- Solubility: DMSO : 13.33 mg/mL (ultrasonic)
- Smiles: CN(C1=CN=C(NC2=C(OCC)C=C(N3CCC(O)CC3)C=C2)N=C1N(C4CCCC4)CC5)C5=O
- Molecular Weight: 480.60
- References & Citations: [1]Kwiatkowski N, et al. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May;6(5):359-68.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported