IP3 Receptor (Phospho Tyr353) rabbit pAb
CAT:
855-ES20180-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IP3 Receptor (Phospho Tyr353) rabbit pAb
- Description: This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],
- Synonyms: Inositol 1, 4, 5-trisphosphate receptor type 1 (IP3 receptor isoform 1;IP3R 1;InsP3R1;Type 1 inositol 1, 4, 5-trisphosphate receptor;Type 1 InsP3 receptor)
- Gene ID: 3708
- UniProt: Q14643
- Cellular Locus: Endoplasmic reticulum membrane ; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum and secretory granules (By similarity)..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from human IP3 Receptor (Phospho Tyr353)
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Molecular Weight: 320kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.