Products for Research Use Only
RegisterLogin

Ocaperidone

CAT: 0804-HY-101094-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101094-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ocaperidone is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively, and a pEC50 and pKi of 7.60 and 8.08 for h5-HT1A.
CAS Number
129029-23-8
Product Name Alternative
R79598
UNSPSC
12352005
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ocaperidone.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C1C(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)=C(C)N=C5N1C=CC=C5C
Molecular Formula
C24H25FN4O2
Molecular Weight
420.48
Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
References & Citations
[1]Leysen JE, et al. In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone. Mol Pharmacol. 1992 Mar;41 (3) :494-508.|[2]Cosi C, et al. Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT (1A) receptors expressed in HeLa cells. Eur J Pharmacol. 2001 Dec 14;433 (1) :55-62.|[3]Rijnders HJ, et al. The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity. Psychopharmacology (Berl) . 1993;111 (1) :55-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor; D2 Receptor; mLAG-3; α-1 microglobulin

Alternative Products

CatalogName
BA5011-10Ocaperidone
A12177-50Ocaperidone 50mg
A12177-25Ocaperidone 25mg
A12177-5Ocaperidone 5mg
A12177-1Ocaperidone 1mg
A12177-100Ocaperidone 100mg
A12177-10Ocaperidone 10mg
A12177-10mM-DOcaperidone 10mM * 1mL in DMSO

Popular Products