Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag | Gentaur

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Product Documents

Datasheet

Alternative Products

Cat	Name
SC126341	ANGPTL3 (untagged)-Human angiopoietin-like 3 (ANGPTL3)
RG208867	ANGPTL3 (GFP-tagged) - Human angiopoietin-like 3 (ANGPTL3)
hAP-1126	Human Angiopoietin-like-Protein-3 (ANGPTL3)
RC208867	ANGPTL3 (Myc-DDK-tagged)-Human angiopoietin-like 3 (ANGPTL3)
MBS6506993-01	Angiopoietin-like 3 (ANGPTL3, ANGPT5)
MBS6506992-02	Angiopoietin-like 3 (ANGPTL3, ANGPT5)
MBS6506992-01	Angiopoietin-like 3 (ANGPTL3, ANGPT5)
MBS6506993-02	Angiopoietin-like 3 (ANGPTL3, ANGPT5)
MG207262	Angptl3 (GFP-tagged) - Mouse angiopoietin-like 3 (Angptl3)
MC201229	Angptl3 (untagged) - Mouse angiopoietin-like 3 (Angptl3), (10ug)

Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag

CAT:

716-AN3-H5253-100ug

Size:

100 µg

Price:

Ask

For price, please contact [email protected].

Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag

Background: Angiopoietin-like protein 3 (ANGPTL3) is also known as Angiopoietin-related protein 3, Angiopoietin-5 (ANGPT5 / ANG-5), is a member of the angiopoietin-like family of secreted factors. ANGPTL3 / ANGPT5 is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Angptl3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. ANGPTL3 inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels. Circulating PL-riched HDL particles have high cholesterol efflux abilities.
Description: Human Angiopoietin-like 3 Protein, Fc Tag (AN3-H5253) is expressed from human 293 cells (HEK293). It contains AA Ser 17 - Glu 460 (Accession # Q9Y5C1-1).
Specifications: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 78.2 kDa. The protein migrates as 65 kDa and 100-115 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Ser 17 - Glu 460
Host: HEK 293
Target: Angiopoietin-like 3
Conjugation: Unconjugated
Tag: C-Fc
Source: Human
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 90%
Bioactivity: Immobilized Human Angiopoietin-like 3 Protein, Fc Tag (Cat. No. AN3-H5253) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human ANGPTL3 Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Format: Powder
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, 0.05% CHAPS, pH7.5
Additives: Trehalose
Molecular Weight: 78.2 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Complementary Product Range

Our range of products, including Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Related Products

Cat	Name
AN3-H52H3-1mg	Human Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-H5253-1mg	Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag
AN3-H5253-100ug	Human Angiopoietin-like 3 / ANGPTL3 Protein, Fc Tag
AN3-H52H3-100ug	Human Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-H5226-100ug	Human Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-H5226-1mg	Human Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-M52H3-1mg	Mouse Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-M52H3-100ug	Mouse Angiopoietin-like 3 / ANGPTL3 Protein, His Tag
AN3-H82E7-25ug	Biotinylated Human Angiopoietin-like 3 / ANGPTL3 Protein, His,Avitag™
AN3-H82E7-200ug	Biotinylated Human Angiopoietin-like 3 / ANGPTL3 Protein, His,Avitag™

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on