Anti-MUC6 (Mucin 6 / Gastric Mucin) (MUC6/1553R), Biotin conjugate
CAT:
37-BNCB1553-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-MUC6 (Mucin 6 / Gastric Mucin) (MUC6/1553R), Biotin conjugate
- Description: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Gastric mucin 6; MUC6; MUC6 mucin; Mucin 6 oligomeric mucus/gel forming; Mucin glycoprotein Fragment; Mucin-6; Secretory mucin MUC6
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: MUC6
- Gene ID: 4588
- NCBI Gene ID: 528432
- UniProt: Q6W4X9
- Cellular Locus: Secreted (extracellular)
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Recombinant full-length human MUC6 protein
- Target Antigen: MUC6
- Clonality: Recombinant Monoclonal
- Isotype: IgG
- Clone: MUC6/1553R
- Conjugation: Biotin
- Disease: Tumor
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Cancer, Mucins
- Positive Control: Human stomach tissue (IHC).
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 252 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years