Phe-Lys(Trt)-PAB

Phe-Lys(Trt)-PAB

• CAS Number: 1116085-99-4
• UNSPSC Description: Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/phe-lys-trt-pab.html
• Purity: 96.24
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: OCC(C=C1)=CC=C1NC([C@@H](NC([C@@H](N)CC2=CC=CC=C2)=O)CCCCNC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O
• Molecular Weight: 640.81
• References & Citations: [1]Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported