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Anti-MRSA agent 20

CAT: 0804-HY-168705Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168705Size:1 Each
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Description
Anti-MRSA agent 20 (Compound a4) is an anti-microbial agent (MIC: MRSA) . Anti-MRSA agent 20 binds to the ribosomal peptidyl transferase center and inhibits bacterial survival by inhibiting MRSA toxin synthesis and bacterial division. Anti-MRSA agent 20 significantly reduces the MRSA load in the lungs and attenuates lung injury in the MRSA-infected mice (ED50 = 6.48 mg/kg) [1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/anti-mrsa-agent-20.html
Smiles
O=C(COC1=C(SCC(O[C@H]2[C@](C)([C@H](C)CC3)[C@]([H])(C(CC4)=O)[C@@]34[C@@H](C)[C@H](O)[C@](C)(C=C)C2)=O)C=CC=C1)N(CC5)CCS5(=O)=O
Molecular Formula
C34H47NO8S2
Molecular Weight
661.87
References & Citations
[1]Yi, et al. Design, synthesis, and biological evaluation of novel pleuromutilin derivatives with methicillin-resistant Staphylococcus aureus -targeting phenol linker groups. European journal of medicinal chemistry, 2025, 282, 117061.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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