Anti-Lewis Y (Tumor Marker) (A70-C/C8)

• Description:

  This antibody recognizes a carbohydrate epitope common to the tumor-associated Lewis Y and Lewis b antigens (Fucalpha1-2Galbeta1-4/3GlcNAcbeta). Its specificity was established without doubt with a panel of 86 synthetic mono- and oligosaccharidic structures. Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

• Synonyms:

  Lewis Y antigen

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  Not Applicable

• UniProt:

  Not Applicable

• Cellular Locus:

  Cytoplasmic|Plasma membrane|Secreted (extracellular)

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Live Ls174T cells (human colon carcinoma cell line)

• Target Antigen:

  Lewis-Y

• Clonality:

  Monoclonal

• Isotype:

  IgM

• Clone:

  A70-C/C8

• Conjugation:

  Purified, with BSA

• Disease:

  Tumor

• Source:

  Animal

• Field of Research:

  Cancer

• Positive Control:

  Lung, Colon, Bladder or Hepatocellular Carcinoma

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight:

  Multiple

• Additionnal Information:

  For coating for ELISA, order Ab without BSA|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4