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SU11652

CAT: 0804-HY-112452-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112452-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research[1].
CAS Number
326914-10-7
UNSPSC
12352005
Target
Apoptosis; c-Kit; FGFR; PDGFR; VEGFR
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su11652.html
Purity
99.18
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=C(Cl)C=C3)=O)=C1C)NCCN(CC)CC
Molecular Formula
C22H27ClN4O2
Molecular Weight
414.93
References & Citations
[1]Liao AT, et al. Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors. Blood. 2002;100 (2) :585-593.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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