Panomifene

• Description :

  Panomifene (EGIS 5650) is a tamoxifen (HY-13757A) analog with an antiestrogenic activity. Panomifene can be used in the research of breast cancer[1][2].

• CAS Number :

  [77599-17-8]

• Product Name Alternative :

  EGIS 5650; GYKI-13504

• UNSPSC :

  12352005

• Target :

  Estrogen Receptor/ERR

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/panomifene.html

• Smiles :

  FC(F)(/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)OCCNCCO)\C3=CC=CC=C3)F

• Molecular Formula :

  C25H24F3NO2

• Molecular Weight :

  427.46

• References & Citations :

  [1]V Erdélyi-Tóth, et al. Determination of panomifene in human plasma by high-performance liquid chromatography. J Chromatogr A. 1994 May 13;668 (2) :419-25.|[2]Tobias Michael Milzarek, et al. Synthesis of Trifluoromethylated Alkenes: Hypervalent Iodine Meets High-Valent Copper. Angew Chem Int Ed Engl. 2023 Aug 14;62 (33) :e202306128.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2