Products for Research Use Only
RegisterLogin

Sauchinone

CAT: 0804-HY-N0613-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0613-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae) . Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity[1].
CAS Number
177931-17-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sauchinone.html
Purity
99.62
Solubility
DMSO : 22.73 mg/mL (ultrasonic)
Smiles
C[C@@H]([C@@H](C[C@]12[H])C)[C@](C(C=C(OCO3)C3=C4)=C4O5)([H])[C@@]1([H])[C@]5(OCO6)C6=CC2=O
Molecular Formula
C20H20O6
Molecular Weight
356.37
Precautions
H302, H315, H319
References & Citations
[1]Lee AK, et al. Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-alpha and COX-2expression by sauchinone effects on I-kappaBalpha phosphorylation, C/EBP and AP-1 activation. Br J Pharmacol. 2003 May;139 (1) :11-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB; RelA/p65

Alternative Products

CatalogName
MBS3840565-01Sauchinone
371942Sauchinone discontinued
A14739-25Sauchinone 25mg
A14739-50Sauchinone 50mg
A14739-10Sauchinone 10mg

Popular Products