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Riselcaftor

CAT: 0804-HY-164037Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164037Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Riselcaftor (Example 33) is a CFTR modulator, with an EC50 of 20.1 nM in human bronchial epithelial cells. Riselcaftor can be used for research of cystic fibrosis[1].
CAS Number
2799652-36-9
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/riselcaftor.html
Smiles
O=S(NC([C@]1(C2=C(C=CC(C)=C2)OC)C[C@H](C3=CC=CC=C3)CO1)=O)(C4=CC=CC5=C4C=CC(C)=N5)=O
Molecular Formula
C29H28N2O5S
Molecular Weight
516.61
References & Citations
[1]David J. Hardee, et al. Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use. Patent. US20220211692 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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