Anti-Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker) (AAT/1378), Biotin conjugate
CAT:
37-BNCB1378-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker) (AAT/1378), Biotin conjugate
- Description: This antibody recognizes a protein of 54 kDa, which is identified as Alpha-1 antitrypsin (AAT). AAT is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Alpha-1 antitrypisin; SERPINA1; Alpha-1 protease inhibitor; Alpha-1 antiproteinase; AAT; Serpin A1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: SERPINA1
- Gene ID: 5265
- NCBI Gene ID: 525557
- UniProt: P01009
- Cellular Locus: Secreted (extracellular)
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment (exact sequence is proprietary)
- Target Antigen: Alpha-1 Antitrypsin
- Clonality: Monoclonal
- Isotype: IgG1
- Clone: AAT/1378
- Conjugation: Biotin
- Disease: Tumor
- Source: Animal
- Applications: IHC, FFPE (verified) | WB (verified)
- Validated Applications: IHC, FFPE, WB
- Field of Research: Cancer, Inflammation
- Positive Control: HepG2 Cells. Tonsil, Hepatocellular Carcinoma or Histiocytoma.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 54 kDa
- Additionnal Information: Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min|Immunofluorescence 0.5-1 ug/mL Western blotting 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Western blotting 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years