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(-) -Sotalol

CAT: 0804-HY-126028-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126028-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Sotalol ((R) -Sotalol) is the R-isomer of Sotalol. (-) -Sotalol is a hERG inhibitor, with a Kd of 0.60 μM. (-) -Sotalol can be used for the research of cardiac arrhythmias[1].
CAS Number
30236-31-8
Product Name Alternative
(R) -Sotalol
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/minus-sotalol.html
Purity
99.00
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CS(=O)(NC1=CC=C(C=C1)[C@H](CNC(C)C)O)=O
Molecular Formula
C12H20N2O3S
Molecular Weight
272.36
References & Citations
[1]DeMarco KR, et, al. Molecular determinants of pro-arrhythmia proclivity of d- and l-sotalol via a multi-scale modeling pipeline. J Mol Cell Cardiol. 2021 Sep;158:163-177.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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