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Vidarabine

CAT: 0804-HY-B0277-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0277-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses[1][2]. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2[2]. Vidarabine also has anti-orthopoxvirus activity[3].
CAS Number
5536-17-4
Product Name Alternative
Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
UNSPSC
12352005
Hazard Statement
H361
Target
Antibiotic; HSV; Nucleoside Antimetabolite/Analog; Orthopoxvirus
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Vidarabine.html
Concentration
10mM
Purity
99.36
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1
Molecular Formula
C10H13N5O4
Molecular Weight
267.25
Precautions
H361
References & Citations
[1]Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20 (4) : p. 267-82.|[2]Suzuki M, et al. Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral Res. 2006;72 (2) :157-161.|[3]Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
HSV-1; HSV-2

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