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15-epi-PGE1

CAT: 0804-HY-116096-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116096-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 but with less biological activity[2]. 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM[1].
CAS Number
20897-91-0
Product Name Alternative
15 (R) -Prostaglandin E1; 15-Epiprostaglandin E1
UNSPSC
12352211
Hazard Statement
H225-H319-H336
Target
15-PGDH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/15-epi-pge1.html
Solubility
10 mM in DMSO
Smiles
OC(CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](O)CCCCC)=O
Molecular Formula
C20H34O5
Molecular Weight
354.48
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Jarabak J, et al., Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. Arch Biochem Biophys. 1976 Nov;177 (1) :245-54. |[2]MURAKAMI A, et al., Conformational analysis of prostaglandins. II. Most probable conformation of prostaglandin A, B, E, and F. Chemical and Pharmaceutical Bulletin. 1977 25 (1) :2870-2874
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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