Human Keratocytes

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Human Keratocytes

CAT:

870-ABC-TC3663

Size:

1 Vial

Price:

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For price, please contact [email protected].

Human Keratocytes

Description: The keratocyte, or corneal fibroblast, is a highly specialized cell that is sandwiched between orthogonally arranged layers of collagen lamellae in the corneal stroma. They play a key role in maintaining the structure and transparency of the cornea as they are the source of stromal collagen and proglycans. They also play important roles in corneal wound healing and tissue repair and are known to undergo phenotypic transformations in wounds due to the influence of growth factors and cytokines. Under normal conditions, the keratocyte in the adult cornea is a relatively quiescent cell. However, in the event of a corneal injury or trauma, the keratocytes differentiate into active, synthesizing cells and rapidly replace damaged stromal matrix. Cultured human keratocytes express functional IL-4Rs and IL-17R on cell surface, suggesting that these cells may contribute to the role of IL-4 and IL-17 as mediators of allergic reactions in the cornea. Changes in gene expression were reproducibly observed on keratocytes after interleukin-1 treatment which provides important insight in gene expression and suggests novel therapeutic targets for the control of corneal inflammation.HK from AcceGen Research Laboratories are isolated from human cornea. HK are cryopreserved at primary culture. Each vial contains >5×10^5 cells in 1 ml volume. HK are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HK are guaranteed to further expand for 15 population doublings at the condition provided by AcceGen Research Laboratories.
Applications: For research use only
Storage Conditions: Liquid Nitrogen

Complementary Product Range

Our range of products, including Human Keratocytes, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
ABC-TC3663	Human Keratocytes
ABC-SC2092	HighQC™ Human IPSC From Activated Fibroblast From Primary Keratocytes-Keratoconus
ABC-TC4015	Human Omental
ABC-TC3831	Human Tenocytes
ABC-TC3734	Human Osteoblast
ABC-TC3646	Human Hepatocytes
ABC-TC3546	Human Cardiomyocytes
ABC-TC3969	Human Astrocytes
ABC-TC3710	Human Monocytes
ABC-TC3722	Human Neurons