TC21/R-Ras2GST Teratocarcinoma oncogene, related ras viral oncogene homolog 2 human, recombinant, E. coli

TC21/R-Ras2GST Teratocarcinoma oncogene, related ras viral oncogene homolog 2 human, recombinant, E. coli

• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. The Ras family of GTP-binding proteins consists of the classical Ras (Ha-, K-, and N-), R-Ras, Rap1, Rap2, Ral, Rheb, Rin, Rit, TC21/R-Ras2, and M-Ras/R-Ras3 (M-Ras). TC21 is a Ras-like GTPase with high oncogenic potential that is found mutated in some human tumors and overexpressed in breast cancer cell lines. TC21 binds physically to c-Raf-1 in a GTP-dependent manner. The GST-Tag facilitates the protein’s application in typical GST pull-down assays.
• CAS Number: 9000-83-3
• UNSPSC: 12352202
• UNSPSC Description: Proteins
• HS Code: 35079090
• Accession Number: NM_012250
• eClass Number: 34160400
• eClass Product Group: Peptide and Protein
• Purity: > 90 % (SDS-PAGE)
• Form: Liquid (Supplied in 25 mM Tris-HCl pH 7.5, 150 mM NaCl, 5 mM MgCl2 and 5 mM beta-mercaptoethanol)
• Autoclavability: false
• Shipping Conditions: Shipped on dry ice.
• Storage Conditions: Store at -80 °C. Avoid freeze/thaw cycles.
• Shelf Life: 12 months