KRasHis - G-domain Kirsten rat sarcoma viral oncogene homolog, G-domain human, recombinant, E. coli

KRasHis - G-domain Kirsten rat sarcoma viral oncogene homolog, G-domain human, recombinant, E. coli

• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signalling and transport pathways. KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. Protein preparation is 100 % GDP-loaded, measured by HPLC. Human K-Ras is a truncated protein containing amino acids 1-163. The 6His-tag is located at the N-terminus.
• CAS Number: 9000-83-3
• UNSPSC: 12352202
• UNSPSC Description: Proteins
• HS Code: 35079090
• Accession Number: NM_004985.3
• eClass Number: 34160400
• eClass Product Group: Peptide and Protein
• Purity: > 90 % (SDS-PAGE)
• Form: Liquid (Supplied in PBS pH 7.5, 5 mM MgCl2 and 50 % glycerol)
• Autoclavability: false
• Shipping Conditions: Shipped on gel packs.
• Storage Conditions: Store at -20 °C. Avoid freeze/thaw cycles.
• Shelf Life: 12 months