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2-Methoxyhydroquinone

CAT: 0804-HY-W013675-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W013675-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Methoxyhydroquinone is a phenolic compound that reduces TNF-α-induced production of chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 64.3 µM. 2-Methoxyhydroquinone is also a precursor in the synthesis of the Hsp90 inhibitor Geldanamycin[2].
CAS Number
824-46-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-methoxyhydroquinone.html
Purity
99.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(O)C=CC(O)=C1
Molecular Formula
C7H8O3
Molecular Weight
140.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Houser KR, et al. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond) . 2012 Mar 13;9:6.|[2]Qin HL, et al. Total synthesis of the Hsp90 inhibitor geldanamycin. Org Lett. 2008 Jun 19;10 (12) :2477-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HSP90

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