Anti-WNT4

• Description :

  The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]

• Reactivity :

  Human

• Immunogen :

  Rabbit polyclonal WNT4(1) antibody was raised against a recombinate human WNT4 protein 156-338aa (BC057781).

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  WB,IHC,ELISA

• Concentration :

  100ug/100ul

• Purity :

  Affinity purified

• Buffer :

  PBS, pH 7.4 with 0.02% sodium azide.

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• CAS Number :

  9007-83-4