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Anti- TNNI2

CAT: 0171-Y058192Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0171-Y058192Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide conjugated to KLH
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,ELISA
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
Rabbit IgG
Specificity
Not tested with other proteins
Applications Notes
For research use only Peptide ELISA titer: 1:40,000-1:80,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end use.

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