Anti-PARP1

• Description :

  This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes

• CAS Number :

  9007-83-4

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide conjugated to KLH

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  WB,ELISA

• Concentration :

  100ug/100ul

• Purity :

  Affinity purified

• Buffer :

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment :

  Rabbit IgG

• Specificity :

  Not yet tested in other species.

• Applications Notes :

  For research use only Peptide ELISA titer: 1:20,000 Western blot analysis: 1:200-1000 Optimal dilutions/concentrations should be determined by the end use