Anti-MMP14

• Description :

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide conjugated to KLH

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  WB,IHC,ELISA

• Concentration :

  100ug/100ul

• Purity :

  Affinity purified

• Buffer :

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment :

  Rabbit IgG

• Applications Notes :

  For research use only Peptide ELISA titer: 1:10,000-1:40,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end use

• CAS Number :

  9007-83-4