Anti-MiTF

CAT: 0171-Y300119Size: 100 µLDry Ice: NoHazardous: No
CAT#:0171-Y300119Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Microphthalmia-associated transcription factor or MiTF is encoded by the MITF gene. This transcription factor has a critical role in neural crest development and differentiation of neural crest derivatives. It is a transcription factor for tyrosinase and tyrosinase-related protein 1 and plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. The MITF gene is important as it regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Diseases such as Waardenburg syndrome type 2 and Tietz syndrome are associated with heterozygous mutations in this gene.
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Recombinant protein corresponding to human MiTF.
Clonality
Monoclonal
Type
Antibodies-Monoclonal
Applications
WB,IP
Concentration
100µg/100µl
Purity
The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Buffer
PBS, pH 7.4 with 0.05% sodium azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG2b
Specificity
Human MiTF.
Applications Notes
WB: 1:250~1:1000. IP: Use at an assay dependent concentration. Optimal dilutions should be calculated by the end user based on their specific application.

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