Anti-EZH2

• Description :

  Enhancer of zeste homolog 2, or EZH2, is encoded by the EZH2 gene. EZH2 helps control transcriptional repression of genes that regulate cell differentiation. This makes the gene a usual target for anti-cancer therapy because it is usually involved in cancer cell proliferation. EZH2 is a gene suppressor so many tumor suppressor genes that are normally turned on are turned off when it becomes overexpressed. Other diseases related to this gene are Weaver syndrome and Ezh2-related overgrowth. EZH2 is useful in the field of cancer research particularly in developing different methods of anti-cancer therapy.

• Reactivity :

  Human

• Immunogen :

  Recombinant peptide within Human EZH2

• Clonality :

  Monoclonal

• Type :

  Antibodies-Monoclonal

• Applications :

  WB,IP

• Concentration :

  100µg/100µl

• Purity :

  The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.

• Buffer :

  PBS, pH 7.4 with 0.05% sodium azide

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment :

  IgG2a

• Specificity :

  Human EZH2

• Applications Notes :

  WB: 1:500~1:2500; IP: Use at 2-10 µg/mg of lysate. Optimal dilutions should be calculated by the end user based on their specific application.

• CAS Number :

  9007-83-4