Anti-CDX2

• Description:

  Caudal Type Homeobox 2 or CDX2 is encoded by the CDX2 gene. CDX2 is an essential regulator of intestine-specific genes involved in cell growth and differentiation. It is expressed in the nuclei of intestinal epithelial cells and it is also involved in early embryonic development of the intestinal tract. Mutations on the CDX2 gene are associated with intestinal inflammation and tumorigenesis as well as diseases including bladder adenocarcinoma and cystic teratoma. As a tool used in diagnostic surgical pathology, CDX2 is useful as a biomarker for intestinal cancer, specifically for colorectal differentiation in the gastrointestinal tract.

• Reactivity:

  Human

• Immunogen:

  Recombinant protein corresponding to human CDX2.

• Clonality:

  Monoclonal

• Type:

  Antibodies-Monoclonal

• Applications:

  WB,Other

• Concentration:

  100µg/100µl

• Purity:

  The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.

• Buffer:

  PBS, pH 7.4 with 0.05% sodium azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG2b

• Specificity:

  Human CDX2

• Applications Notes:

  WB: 1:500~1:2000. Optimal dilutions should be calculated by the end user based on their specific application.

• CAS Number:

  9007-83-4