Anti-CD2AP

• Description:

  This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  Rabbit polyclonal CD2AP antibody was raised against a peptide from C terminal residues of human CD2AP protein.

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  IHC,ELISA

• Concentration:

  100ug/100ul

• Purity:

  Affinity purified

• Buffer:

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG

• Applications Notes:

  For research use only Peptide ELISA titer: 1:5,000-1:10,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use.

• CAS Number:

  9007-83-4