Anti-ATF1

• Description :

  This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]

• CAS Number :

  9007-83-4

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide conjugated to KLH

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  WB,ELISA

• Concentration :

  100ug/100ul

• Purity :

  Purified

• Buffer :

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment :

  Rabbit IgG

• Specificity :

  ATF1 antibody detects endogenous levels of ATF1 protein. Not tested with other proteins

• Applications Notes :

  Recommended dilutions Peptide ELISA: 1:40,000 WB: 1/500 - 1/1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user