Anti-APEX2

CAT: 0171-Y058378Size: 100 µLDry Ice: NoHazardous: No
CAT#:0171-Y058378Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Rabbit polyclonal APEX2 antibody was raised against a peptide at the C terminal residues of human APEX2 protein.
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
IHC,ELISA
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Applications Notes
For research use only Peptide ELISA titer: 1:1,000-1:10,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use

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