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Anti-ANTXR1

CAT: 0171-Y158183Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0171-Y158183Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
Rabbit polyclonal ANTXR1 (1) antibody was raised against a recombinate human ANTXR1 protein 19-196aa (BC012074).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,IHC,ELISA
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Specificity
Human and predicted against mouse and rat.

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