Anti-AMACR

• Description :

  This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide conjugated to KLH

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  WB,ELISA

• Concentration :

  100ug/100ul

• Purity :

  Protein A purified

• Buffer :

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment :

  Rabbit IgG

• Specificity :

  AMACR antibody detects endogenous levels of AMACR protein. Not tested with other proteins

• Applications Notes :

  Recommended dilutions Peptide ELISA: 1:80,000 WB: 1/500 - 1/1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user

• CAS Number :

  9007-83-4