Anti-ADAM-17

• Description:

  The ADAM17 (a disintegrin and metalloprotease (ADAM) domain 17) is a member of the ADAM proteinfamily. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The ADAM17 functionsas a tumor necrosis factor-alpha converting enzyme.It binds mitotic arrest deficient 2 protein and also plays a prominent role in the activation of the Notch signaling pathway

• Reactivity:

  Human

• Immunogen:

  Rabbit polyclonal ADAM17 antibody was raised against a peptide from near the C terminal residues of human ADAM17 protein.

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  ELISA

• Concentration:

  100ug/100ul

• Purity:

  Affinity purified

• Buffer:

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG

• Applications Notes:

  For research use only Peptide ELISA titer: 1:1,000-1:10,000 Western blot analysis: 1:200-1,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use.

• CAS Number:

  9007-83-4