Anti-ACVR2A

• Description:

  This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  Rabbit polyclonal ACVR2A (1) antibody was raised against a recombinate human ACVR2A protein 45-305aa (BC069707).

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  Other

• Concentration:

  100ug/100ul

• Purity:

  Affinity purified

• Buffer:

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Specificity:

  Human and predicted against mouse and rat.

• CAS Number:

  9007-83-4