Anti-TRPC6

• Description:

  The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  The antibody was produced against a synthesized peptide Corresponding to the amino terminal sequence from mouse TRPC6 protein (-RRNESQDYLLMDELG-).

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  WB

• Concentration:

  100ug/100ul

• Purity:

  Affinity purified

• Buffer:

  Rabbit IgG in phosphate buffered saline (without Mg²+ and Ca²+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG

• Specificity:

  TRPC6 antibody detects endogenous levels of total TRPC6 protein.

• Applications Notes:

  WB: 1:500~1:1000

• CAS Number:

  9007-83-4