Anti-JAK2 (Phospho-Tyr221)

• Description:

  This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  IHC

• Concentration:

  1ug/ul

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

• Buffer:

  phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Specificity:

  JAK2 (phospho-Tyr221) antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 221.

• Applications Notes:

  IHC: 1:50~1:100

• CAS Number:

  9007-83-4