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Anti-hBUB1

CAT: 0171-Y120001Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Y120001Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The BUB family of serine/threonine kinases is a major target of oncology therapeutic research and development. hBUB1 and hBUBR1 are kinases that associate with hBUB3 and are essential components of the mitotic checkpoint. hBUBR1 appears to provide two checkpoint functions by monitoring CENP-E-dependent activities at the kinetochore and by regulating cyclosome/APC activity.hBUBR1 is required in order for microtubule inhibitors to arrest cells in mitosis. Non-mutational inactivation of hBUB1 and hBUBR1 appear related to stage of colon cancer and could be related to aneuploidy in human colorectal and other cancers.
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Purified ascites.
Clonality
Monoclonal
Clone
P8.14H5.1H1
Type
Antibodies-Monoclonal
Applications
WB,IP,ICC/IF
Concentration
100ug/100ul
Purity
Purified ascites.
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG1
Applications Notes
Titrate for optimal dilution for your application.

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Alternative Products

CatalogName
GTR18084300Anti-hBUB1
MBS417798-01Anti-hBUB1 Antibody
207520BUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1)
207520-HRPBUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) (HRP)
207520-FITCBUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) (FITC)
207520-PEBUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) (PE)
207520-BiotinBUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) (Biotin)
B2790-01BUB1 (Bub1L, hBub1, BublL, Budding uninhibited by benzimidazoles 1-like)
207520-APCBUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) (APC)
MBS6140060-01BUB1 (Budding Uninhibited by Benzimidazoles 1, BUB1A, BUB1L, HBUB1) APC

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