Anti-cdc25C (Ab16)

• Description :

  This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

• Reactivity :

  Human

• Immunogen :

  The antiserum was produced against synthesized non-phosphopeptide derived from human cdc25C around the phosphorylation site of serine 216 (S-P-SP-M-P).

• Clonality :

  Polyclonal

• Type :

  Antibodies-Polyclonal

• Applications :

  IHC

• Concentration :

  1ug/ul

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Buffer :

  phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Shipping Conditions :

  Ice Pack

• Storage Conditions :

  This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Specificity :

  cdc25C (Ab-216) antibody detects endogenous levels of total cdc25C protein.

• Applications Notes :

  IHC: 1:50~1:100

• CAS Number :

  9007-83-4