Glycine (Standard)

CAT:

804-HY-Y0966R-04

Size:

10 mg

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Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Glycine (Standard)

CAS Number: 56-40-6
UNSPSC Description: Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis[1][2][3][4][5][6].
Target Antigen: Endogenous Metabolite; iGluR; VEGFR
Type: Reference Standards
Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Protein Tyrosine Kinase/RTK
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/glycine-standard.html
Purity: 98.00
Smiles: NCC(O)=O
Molecular Weight: 75.07
References & Citations: [1]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.|[2]Fone KCF, et al. Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management. Mol Neurobiol. 2020 May;57(5):2144-2166. |[3]Bruns H, et al. Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells. Amino Acids. 2016 Nov;48(11):2549-2558. |[4]Borges JP, et al. Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. Elife. 2022 Dec 5;11:e78609. |[5]Shafiekhani M, et al. Glycine supplementation mitigates lead-induced renal injury in mice. J Exp Pharmacol. 2019 Feb 18;11:15-22. |[6]Bannai M, et al. Oral administration of glycine increases extracellular serotonin but not dopamine in the prefrontal cortex of rats. Psychiatry Clin Neurosci. 2011 Mar;65(2):142-9.
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)

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396	5-ROX glycine Fluorescence reference standard for PCR reactions
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