Recombinant Mouse MEC (CCL28)

Recombinant Mouse MEC (CCL28)

• Description: The mucosa-associated epithelial chemokine CCL28 is a common mucosal chemokine which is constitutively expressed by epithelial cells in most mucosal sites. Both CCL28 and CCL25 have recently been shown to be essential for lymphocyte migration to gastrointestinal tissues. CCL28 attracts IgA ASC, but not IgG or IgM ASC, from both intestinal and extraintestinal mucosal tissue, while CCL25 preferentially attracts IgA ASC from the small intestine and its draining lymphoid tissues, as well as alpha-4-beta-7(+) T cells.
• CAS Number: 9000-83-3
• Gene Name: CCL28
• Gene Aliases: C-C motif chemokine 28, Small-inducible cytokine A28, Scya28, Ccl28
  Recombinant Mouse Mucosae-Associated Epithelial Chemokine (CCL28)
• Gene ID: 56838
• Accession Number: Q9JIL2
• Organism: Mouse
• Source: E. coli
• Concentration: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: >95% as determined by SDS-PAGE
• Solubility: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
• Function: Determined by the ability to chemoattract human lymphocytes using a concentration range of 2-10 ng/mL.
• Molecular Weight: 12
• Shipping Conditions: Ambient Temperature
• Storage Conditions: Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Appearance: Lyophilized Powder
• Formulation: Recombinant CCL-28 was lyophilized from PBS pH 7.4.