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Recombinant Mouse LIX (CXCL5)

CAT: 0171-Z200559Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z200559Size:1 mg
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Description
Epithelial neutrophil- activating protein 78 (ENA-78) is a member of the CXC chemokines and acts as a potent chemoattractant and activator of neutrophil function. On stimulation in vitro, ENA-78 is highly expressed in many cell types. ENA-78 protein levels are strongly elevated in synovial fluid and blood of patients with rheumatoid arthritis. By in situ hybridization and immunofluorescence staining, ENA-78 has been recognized as a major CXC chemokine expressed in epithelial cells of the intestinal mucosa of patients with Crohn's disease, ulcerative colitis, and acute appendicitis.
CAS Number
9000-83-3
Gene Name
CXCL5
Gene Aliases
C-X-C motif chemokine 5, Cytokine LIX, Small-inducible cytokine B5
Gene ID
20311
Accession Number
P50228
Organism
Mouse
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract human neutrophils using a concentration range of 2.0-40 ng/mL.
Molecular Weight
11
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in 20 mM PB,100 mM NaCl pH 7.5.