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Recombinant Mouse IL25

CAT: 0171-Z200257Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Z200257Size:100 µg
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Description
IL-25 (also known as IL- 17E), a member of the IL-17 family, has been implicated in Th2 cell-mediated immunity. Recently, IL-25 has been identified as one of the initiators of the Th2 response (10, 11) and has also been shown to be expressed by mast cells. The transgenic overexpression of IL-25 by lung epithelial cells results in mucus hyperproduction and airway infiltration of macrophages and eosinophils; conversely, IL-25 blockade reduced airway inflammation and Th2 cytokine production in an allergen-induced asthma model.
CAS Number
9000-83-3
Gene Name
IL25
Gene Aliases
UPF0556 protein, IL-25, Stromal cell-derived growth factor SF20, D17Wsu104e, Il25
Recombinant Mouse Interleukin-25 (IL25)
Gene ID
140806
Accession Number
Q9CPT4
Organism
Mouse
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL.
Molecular Weight
16
Shipping Conditions
Ambient Temperature
Storage Conditions
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from 0.2μm filtered solution in Tris and NaCl

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